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What is the difference between Hepatitis B and Hepatitis C?

What is the difference between Hepatitis B and Hepatitis C?

Relevance: GS Prelims – Health / Diseases / Government Schemes & Programmes / SDGs

About Viral Hepatitis

  • Hepatitis refers to inflammation of the liver, most commonly caused by viral infection.
  • There are five main types of hepatitis viruses: A, B, C, D, and E.
  • Hepatitis B and C are the major causes of chronic liver disease, cirrhosis, and liver cancer globally and are the primary focus of India’s NVHCP.
  • Both are often referred to as “silent killers” due to their largely asymptomatic progression, delaying diagnosis and treatment.

Hepatitis B — Key Facts

  • Caused by the Hepatitis B Virus (HBV), a DNA virus.
  • Transmitted through:
    ○ Blood and body fluids
    Mother-to-child (perinatal) transmission
    ○ Unsafe sexual contact
    ○ Unsafe injections
  • A vaccine is available and was introduced under the Universal Immunization Programme (UIP) in 2011.
  • India’s Hepatitis B birth-dose coverage has crossed 92%.
  • Newborns of Hepatitis B-positive mothers are administered Hepatitis B Immunoglobulin (HBIG) within 24 hours of birth.
  • Chronic infection can lead to cirrhosis and hepatocellular carcinoma (liver cancer).
  • Under NVHCP, India provides free-of-cost management of Hepatitis B (not fully curable, but manageable through antivirals).

Hepatitis C — Key Facts

  • Caused by the Hepatitis C Virus (HCV), an RNA virus.
  • Transmitted primarily through:
    Blood-to-blood contact
    ○ Unsafe injections and needle-sharing
    ○ Unscreened blood transfusions
  • No vaccine is currently available for Hepatitis C.
  • High-risk groups include Injecting Drug Users (IDUs).
  • India is among the few countries providing free-of-cost treatment for Hepatitis C.
  • Treated using Direct-Acting Antivirals (DAAs); the disease is curable in most cases with short-course therapy.
  • Cost of medicines under NVHCP has been reduced to less than one dollar.

Key Distinguishing Points

  • Hepatitis B → vaccine-preventable, chronic but not typically curable, managed lifelong.
  • Hepatitis C → no vaccine, but curable with DAA treatment.
  • Hepatitis A and E (not covered under NVHCP) spread via the faecal-oral route (contaminated food/water) and are usually self-limiting.

Government Response

  • Both Hepatitis B and C are covered under the National Viral Hepatitis Control Programme (NVHCP).
  • NVHCP converges with the Reproductive and Child Health (RCH) Programme, National AIDS Control Programme (NACO), and Universal Immunization Programme.
  • Patient tracking done via the Case-Based Management Information System (CPMIS), integrated with the Ayushman Bharat Digital Mission (ABDM).

SDG Linkage

  • Elimination of Hepatitis B and C as public health threats by 2030 aligns with SDG Target 3.3.

Conclusion

While Hepatitis B and C share overlapping transmission routes and health consequences, they differ fundamentally in preventability (vaccine availability) and curability, shaping India’s differentiated public health strategy — vaccination-driven prevention for Hepatitis B and treatment-driven elimination for Hepatitis C — under the NVHCP framework.

This concept has been elaborately discussed in the following article

World Hepatitis Day 2026 & National Viral Hepatitis Control Programme (NVHCP).  
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