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What is H1N1 INFLUENZA?

What is H1N1 INFLUENZA?

About

  • H1N1 is a subtype of Influenza A virus that can cause respiratory illness in humans.
  • The virus is commonly associated with influenza (flu) and can range from mild to severe respiratory disease.
  • H1N1 is an RNA virus belonging to the Orthomyxoviridae family.

Why is it Called H1N1?

  • The name H1N1 is based on two surface proteins present on the virus: Haemagglutinin (H) and Neuraminidase (N).
  • H1 refers to the type of haemagglutinin, while N1 refers to the type of neuraminidase.
  • These surface proteins are important for viral entry, replication and spread.

2009 H1N1 Pandemic

  • A novel H1N1 influenza virus emerged in 2009 and caused a global influenza pandemic.
  • The 2009 pandemic virus contained genetic material derived from human, avian and swine influenza viruses.
  • It was initially popularly called “swine flu”, although the pandemic virus was not simply a virus transmitted directly from pigs.

Transmission

  • H1N1 primarily spreads through respiratory droplets and aerosols released when an infected person coughs, sneezes or talks.
  • Transmission can also occur through contaminated hands or surfaces followed by touching the nose, mouth or eyes.
  • It can spread from person to person.

Major Symptoms

  • Common symptoms include fever, cough, sore throat, headache, body aches, fatigue and runny or stuffy nose.
  • Severe infection can lead to pneumonia and respiratory complications, particularly in vulnerable individuals.

H1N1 and Pigs

  • Pigs can be infected with influenza A viruses, including viruses of different genetic origins.
  • Pigs can sometimes become infected with more than one influenza virus, allowing genetic reassortment to occur.
  • This makes swine populations important in the ecology and evolution of influenza viruses.

Conclusion

H1N1 is an Influenza A virus subtype whose pandemic potential is linked to its ability to undergo genetic changes, including reassortment, making influenza surveillance and preparedness important.

This concept has been elaborately discussed in the following article:

H1N1 Alert: Why ICMR Says There Is No Cause for Panic