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Maternal Genes Determine Left- and Right-Handed Shell Coiling in Snails

Maternal Genes Determine Left- and Right-Handed Shell Coiling in Snails

Context

Recently, scientists from the United Kingdom and Japan identified the role of an unconventional myosin gene in determining the left- or right-handed shell coiling in Japanese Euhadra snails.

About Shell Handedness in Snails

  • Meaning: Shell handedness refers to the direction in which a snail’s shell coils.
  • Types:
    • Dextral (Right-handed): The shell coils towards the right.
    • Sinistral (Left-handed): The shell coils towards the left.
  • Most Euhadra snail species are right-handed, while only four species are predominantly left-handed.
  • Opposite-handed snails face difficulties during mating because their reproductive openings are positioned asymmetrically, making successful mating difficult.

Genetic Basis of Shell Handedness

  • Responsible Gene: An unconventional myosin gene plays a key role in determining shell coiling direction.
  • Researchers identified two variants of this gene:
    • S Variant (Sinistral): Associated with left-handed shell coiling.
    • D Variant (Dextral): Associated with right-handed shell coiling.

Role of Maternal Effect

  • Snail handedness is determined by the mother’s genotype, not directly by the offspring’s own genotype.
  • This is known as the maternal effect, in which the mother’s genetic makeup influences the development of her offspring.
  • The determination occurs at a very early embryonic stage, before the offspring’s own genes begin to express themselves.

About Myosin Protein

  • Myosin is a motor protein that interacts with actin filaments to generate mechanical force and movement within cells.
  • It plays an important role in:
    • Muscle contraction and body movement.
    • Cell division.
    • Cell movement and intracellular transport.
  • Different variants of myosin may influence the direction of actin filament movement, contributing to cellular asymmetry.

Reproductive Characteristics of Snails

  • Hermaphrodites: Snails possess both male and female reproductive organs and can produce sperm and eggs.
  • Genital Pore: The reproductive opening is generally located close to the head, on the right side of the body.
  • Mating: During mating, two snails exchange sperm through their reproductive organs.

Significance of the Discovery

  • Explains how genetic variations can influence left-right asymmetry during embryonic development.
  • Provides insights into the relationship between molecular mechanisms and whole-body structural organisation.
  • Helps understand the role of motor proteins in cellular development and evolutionary biology.
  • Establishes snails as an important model for studying the origin of biological asymmetry.
Important CTC From This Article:

Myosin  
Q. With reference to shell handedness in snails, consider the following statements:

1. The direction of shell coiling in Euhadra snails is determined exclusively by the offspring's own genetic makeup.
2. The S variant of the myosin gene is associated with left-handed shell coiling.
3. Myosin interacts with actin filaments and plays a role in generating mechanical force within cells.
4. Snails are generally hermaphrodites, possessing both male and female reproductive organs.

Which of the statements given above are correct?

(a) 1 and 2 only
(b) 2, 3 and 4 only
(c) 1, 3 and 4 only
(d) 1, 2, 3 and 4

Answer: (b) 2, 3 and 4 only

Explanation:
Statement 1 is incorrect:
Shell handedness in Euhadra snails is determined by the mother's genotype rather than directly by the offspring's own genotype. This phenomenon is known as the maternal effect.
Statement 2 is correct: Researchers identified two variants of the myosin gene. The S (sinistral) variant is associated with left-handed shell coiling, while the D (dextral) variant is associated with right-handed shell coiling.
Statement 3 is correct: Myosin is a motor protein that interacts with actin filaments to generate mechanical force. It plays important roles in muscle contraction, cell movement and cell division.
Statement 4 is correct: Snails are generally hermaphrodites, meaning that an individual possesses both male and female reproductive organs and can produce sperm and eggs.